Perforin PromoFluor 488P (Pf-344, Mouse) - Reactivity: Human, Non-Human Primate, Porcine
Product Details
| Description | anti-human Perforin mAb Pf-344, PF647P | |
|---|---|---|
| Conjugate | PromoFluor 488P | |
| Clone | Pf-344 | |
| Target Species | Human, Non-Human Primate, Porcine | |
| Applications | FC | |
| Supplier | Mabtech | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Perforin
This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
About PromoFluor 488P
PromoFluor 488P is a fluorophore with an excitation peak at 490 nm and an emission peak at 516 nm. It is equivalent to Alexa Fluor™ 488 and DyLight™ 488 in size, brightness and application. It can be used with the following analysis platforms: Flow Cytometry and Fluorescence Microscopy.
PromoFluor 488P is a fluorophore with an excitation peak at 490 nm and an emission peak at 516 nm. It is equivalent to Alexa Fluor™ 488 and DyLight™ 488 in size, brightness and application. It can be used with the following analysis platforms: Flow Cytometry and Fluorescence Microscopy.
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